Clinical Epigenetics

Title Publication Date Language Citations
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes2020/11/23English62
Promoter methylation of SEPT9 as a potential biomarker for early detection of cervical cancer and its overexpression predicts radioresistance2019/08/19English62
The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus2015/03/14English62
H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia2018/04/10English62
DNA methylation of the IGF2/H19 imprinting control region and adiposity distribution in young adults2012/11/13English61
Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients2015/11/05English61
Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome2019/04/27English60
The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain2015/05/27English60
Control of viral infections by epigenetic-targeted therapy2019/03/27English60
Distinct DNA methylation profiles in subtypes of orofacial cleft2017/06/08English60
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes2021/07/08English59
Insulin-like growth factor axis in pregnancies affected by fetal growth disorders2016/01/27English59
TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus2016/04/05English59
Hypomethylation and overexpression of ITGAL (CD11a) in CD4+ T cells in systemic sclerosis2014/11/11English58
Effects of phthalate exposure on asthma may be mediated through alterations in DNA methylation2015/03/15English58
DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer2018/08/06English58
Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma2017/02/10English58
DNA methylation as a predictor of fetal alcohol spectrum disorder2018/01/12English58
Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy2016/09/05English58
Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations2016/10/12English58
Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study2018/04/18English58
DNA methylation signature of human hippocampus in Alzheimer’s disease is linked to neurogenesis2019/06/19English58
The epigenetic implication in coronavirus infection and therapy2020/10/21English57
Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children2012/09/25English57
Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth2017/05/08English57
Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy2015/03/29English57
Polycomb repressive complex’s evolutionary conserved function: the role of EZH2 status and cellular background2016/05/27English57
PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newborns2016/06/22English57
Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH22019/02/14English57
Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study2018/02/09English56