Title	Publication Date	Language	Citations
H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues	2011/06/25	English	86
Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis	2015/08/04	English	84
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer	2018/06/15	English	84
Methylation analysis and diagnostics of Beckwith-Wiedemann syndrome in 1,000 subjects	2014/06/04	English	82
Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders	2017/06/29	English	82
Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants	2015/04/24	English	80
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health	2018/10/20	English	80
DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application	2021/08/27	English	79
Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden	2020/07/31	English	79
MicroRNA-375 plays a dual role in prostate carcinogenesis	2015/04/10	English	78
Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia	2018/04/10	English	78
Epigenetic features of FoxP3 in children with cow’s milk allergy	2016/08/12	English	78
Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study	2017/02/07	English	78
Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study	2019/11/14	English	77
Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA	2019/03/15	English	76
Polycomb-mediated silencing in neuroendocrine prostate cancer	2015/04/03	English	76
Epigenetic control of HIV-1 post integration latency: implications for therapy	2015/09/24	English	75
Epigenetic signatures of gestational diabetes mellitus on cord blood methylation	2017/03/27	English	75
Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism	2019/07/12	English	75
DNA methylation differences between in vitro- and in vivo-conceived children are associated with ART procedures rather than infertility	2015/04/08	English	74
Circulating microRNA-144-5p is associated with depressive disorders	2015/07/22	English	74
DNA methylation links prenatal smoking exposure to later life health outcomes in offspring	2019/07/01	English	73
Epigenetic understanding of gene-environment interactions in psychiatric disorders: a new concept of clinical genetics	2012/01/20	English	72
The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years	2013/01/03	English	71
Differential placental methylation and expression of VEGF, FLT- 1 and KDR genes in human term and preterm preeclampsia	2013/04/26	English	71
Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix	2012/08/31	English	70
Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans	2015/06/10	English	70
Epigenetic mechanisms and genome stability	2010/12/29	English	69
Global DNA methylation levels are altered by modifiable clinical manipulations in assisted reproductive technologies	2017/02/06	English	69
Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer	2018/04/11	English	69