Chemical Research in Toxicology

Title Publication Date Language Citations
Retrospective Detection of Exposure to Organophosphorus Anti-Cholinesterases:  Mass Spectrometric Analysis of Phosphylated Human Butyrylcholinesterase2002/03/22English157
Trivalent Arsenicals Are Bound to Proteins during Reductive Methylation2006/07/19English156
Biotransformation of N-Ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by Rat Liver Microsomes, Cytosol, and Slices and by Expressed Rat and Human Cytochromes P4502004/05/01English156
Subchronic Exposure of Mice to Cadmium Perturbs Their Hepatic Energy Metabolism and Gut Microbiome2015/09/15English156
Reactive Metabolites in the Biotransformation of Molecules Containing a Furan Ring2012/10/24English155
Interactions of Nitrogen-Containing Xenobiotics with Monoamine Oxidase (MAO) Isozymes A and B:  SAR Studies on MAO Substrates and Inhibitors2001/07/20English154
ZnO Particulate Matter Requires Cell Contact for Toxicity in Human Colon Cancer Cells2010/02/15English153
Nitroxidative, Nitrosative, and Nitrative Stress:  Kinetic Predictions of Reactive Nitrogen Species Chemistry Under Biological Conditions2006/08/18English153
Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease2014/12/26English153
Biotransformation of the Naturally Occurring Isothiocyanate Sulforaphane in the Rat:  Identification of Phase I Metabolites and Glutathione Conjugates1997/11/01English152
Formation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine by Lipid Peroxidation Products and Nucleic Acid Bases1995/03/01English152
Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment2011/03/08English152
Apple Polyphenols, Phloretin and Phloridzin: New Trapping Agents of Reactive Dicarbonyl Species2008/09/06English151
Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin1992/05/01English150
Covalent Modification at Cys151 Dissociates the Electrophile Sensor Keap1 from the Ubiquitin Ligase CUL32008/02/06English150
Contact Allergens Formed on Air Exposure of Linalool. Identification and Quantification of Primary and Secondary Oxidation Products and the Effect on Skin Sensitization2004/11/25English149
Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies2008/08/15English149
Nitrotyrosine−Protein Adducts in Hepatic Centrilobular Areas following Toxic Doses of Acetaminophen in Mice1998/05/23English149
Negative Ion Tandem Mass Spectrometry for the Detection of Glutathione Conjugates2005/03/09English149
In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs2012/05/31English148
Detection of Weak Estrogenic Flavonoids Using a Recombinant Yeast Strain and a Modified MCF7 Cell Proliferation Assay1998/05/27English147
The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA2007/12/04English147
Applying Mechanisms of Chemical Toxicity to Predict Drug Safety2007/02/16English147
Hypochlorite-Induced Damage to DNA, RNA, and Polynucleotides:  Formation of Chloramines and Nitrogen-Centered Radicals2002/01/01English147
Arsenic-Induced Carcinogenesis—Oxidative Stress as a Possible Mode of Action and Future Research Needs for More Biologically Based Risk Assessment2009/12/28English146
Oxidation of Benzo[a]pyrene by Recombinant Human Cytochrome P450 Enzymes1995/01/01English146
Inhibition of Human Cytochrome P450 1A1-, 1A2-, and 1B1-Mediated Activation of Procarcinogens to Genotoxic Metabolites by Polycyclic Aromatic Hydrocarbons2006/01/24English145
Characterization of Hydantoin Products from One-Electron Oxidation of 8-Oxo-7,8-dihydroguanosine in a Nucleoside Model2001/05/23English145
The Physiological Chemistry and Biological Activity of Nitroxyl (HNO):  The Neglected, Misunderstood, and Enigmatic Nitrogen Oxide2005/04/02English143
Ligand-Based Identification of Environmental Estrogens1996/01/01English143