Chemical Research in Toxicology

Title Publication Date Language Citations
Metabolism of Arsenic in Primary Cultures of Human and Rat Hepatocytes1999/06/24English91
Advancing Computational Toxicology in the Big Data Era by Artificial Intelligence: Data-Driven and Mechanism-Driven Modeling for Chemical Toxicity2019/03/14English90
Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity2006/03/25English90
Peroxynitrous Acid Homolyzes into •OH and •NO2 Radicals1998/07/01English90
Protein Reactivity of 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite, Is Dependent on Both the Aldehyde and the Catechol2009/06/19English90
Three Novel Hydroxybenzoate Saxitoxin Analogues Isolated from the Dinoflagellate Gymnodinium catenatum2003/07/29English90
Mercury Binding to the Chelation Therapy Agents DMSA and DMPS and the Rational Design of Custom Chelators for Mercury2004/07/22English90
Toxic Metals and Autophagy2014/10/13English90
Can Graphene Oxide Cause Damage to Eyesight?2012/05/25English89
Endogenous Reductants Support the Catalytic Function of Recombinant Rat Cyt19, an Arsenic Methyltransferase2004/02/14English89
Quantitation of DNA Adducts by Stable Isotope Dilution Mass Spectrometry2012/08/28English89
Quantifying Processes Determining the Free Concentration of Phenanthrene in Basal Cytotoxicity Assays2012/02/08English89
Highly Reactive Free Radicals in Electronic Cigarette Aerosols2015/08/07English89
Toxic Effects of Imidazolium Ionic Liquids on the Green Seaweed Ulva lactuca: Oxidative Stress and DNA Damage2011/10/06English89
Epigenetic Reactivation of Nrf2 in Murine Prostate Cancer TRAMP C1 Cells by Natural Phytochemicals Z-Ligustilide and Radix Angelica Sinensis via Promoter CpG Demethylation2013/03/08English89
Mechanisms of Toxicity of Amorphous Silica Nanoparticles on Human Lung Submucosal Cells in Vitro: Protective Effects of Fisetin2012/09/19English89
DNA Lesions Derived from the Site Selective Oxidation of Guanine by Carbonate Radical Anions2003/10/28English89
Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[a,l]pyrene1998/05/05English88
Big Data in Chemical Toxicity Research: The Use of High-Throughput Screening Assays To Identify Potential Toxicants2014/09/16English88
Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N2-Ethyldeoxyguanosine2006/01/12English88
In Vitro Metabolism of Tolcapone to Reactive Intermediates:  Relevance to Tolcapone Liver Toxicity2003/01/30English88
Exploring the Biology of Lipid Peroxidation-Derived Protein Carbonylation2011/08/18English88
Reversibility of Covalent Electrophile−Protein Adducts and Chemical Toxicity2008/10/21English88
Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species2009/12/16English88
Albumin Is the Main Nucleophilic Target of Human Plasma: A Protective Role Against Pro-atherogenic Electrophilic Reactive Carbonyl Species?2008/03/07English87
Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene:  Irreversible Enzyme Inhibition and Thiol Adduct Formation2002/06/07English87
Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids:  Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A22001/07/24English87
Photoprotective Actions of Natural and Synthetic Melanins1998/10/22English87
Sources and role of iron in lipid peroxidation1993/03/01English87
Bile Acids Metabonomic Study on the CCl4- and α-Naphthylisothiocyanate-Induced Animal Models: Quantitative Analysis of 22 Bile Acids by Ultraperformance Liquid Chromatography−Mass Spectrometry2008/11/24English87