Chemical Research in Toxicology

Title Publication Date Language Citations
Exposure and Kinetics of Polycyclic Aromatic Hydrocarbons (PAHs) in Cigarette Smokers2012/03/29English99
Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress2009/03/23English99
Dominant Contribution of P450 3A4 to the Hepatic Carcinogenic Activation of Aflatoxin B12006/03/24English99
Arsenic at Very Low Concentrations Alters Glucocorticoid Receptor (GR)-Mediated Gene Activation but Not GR-Mediated Gene Repression:  Complex Dose−Response Effects Are Closely Correlated with Levels of Activated GR and Require a Functional GR DNA Binding Domain2004/07/16English98
Reactions of Nitric Oxide with Metalloproteins1996/01/01English98
Geometric Trajectory Analysis of Metabolic Responses To Toxicity Can Define Treatment Specific Profiles2004/04/15English98
Regioselectivity and Reversibility of the Glutathione Conjugation of Quercetin Quinone Methide2000/03/01English98
Ochratoxin A:  Lack of Formation of Covalent DNA Adducts2004/01/23English97
Analysis of DNA Adducts of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Rat and Human Tissues by Alkaline Hydrolysis and Gas Chromatography/Electron Capture Mass Spectrometry: Validation by Comparison with 32P-Postlabeling1994/11/01English97
A predictive model for substrates of cytochrome P450-debrisoquine (2D6)1992/03/01English97
Arsenic Metabolism and Thioarsenicals in Hamsters and Rats2007/03/24English97
Inhibition of Human Mitochondrial Aldehyde Dehydrogenase by 4-Hydroxynon-2-enal and 4-Oxonon-2-enal2005/12/23English97
Covalent Modifications to 2‘-Deoxyguanosine by 4-Oxo-2-nonenal, a Novel Product of Lipid Peroxidation1999/11/06English96
Failure of MTT as a Toxicity Testing Agent for Mesoporous Silicon Microparticles2007/11/09English96
Comparison of the Formation of 8-Hydroxy-2‘-deoxyguanosine and Single- and Double-Strand Breaks in DNA Mediated by Fenton Reactions1998/04/17English96
Glutathione conjugation of aflatoxin B1 exo- and endo-epoxides by rat and human glutathione S-transferases1992/07/01English96
Kinetics of S-Nitrosation of Thiols in Nitric Oxide Solutions1996/01/01English96
Chiral Inversion and Hydrolysis of Thalidomide:  Mechanisms and Catalysis by Bases and Serum Albumin, and Chiral Stability of Teratogenic Metabolites1998/11/06English95
Alterations in Gene Expression Induced by the Lipid Peroxidation Product, 4-Hydroxy-2-nonenal2005/11/01English95
First Principles Calculations of the Tautomers and pKaValues of 8-Oxoguanine:  Implications for Mutagenicity and Repair2002/08/01English95
Synthesis and characterization of estrogen 2,3- and 3,4-quinones. Comparison of DNA adducts formed by the quinones versus horseradish peroxidase-activated catechol estrogens1992/11/01English95
Identification and quantitation of benzo[a]pyrene-DNA adducts formed in mouse skin1993/05/01English95
Kinetic Glutathione Chemoassay To Quantify Thiol Reactivity of Organic Electrophiles—Application to α,β-Unsaturated Ketones, Acrylates, and Propiolates2009/03/25English95
Mechanism of Dithiocarbamate Inhibition of Apoptosis:  Thiol Oxidation by Dithiocarbamate Disulfides Directly Inhibits Processing of the Caspase-3 Proenzyme1997/06/01English95
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments2016/01/06English95
α-Terpinene, an Antioxidant in Tea Tree Oil, Autoxidizes Rapidly to Skin Allergens on Air Exposure2012/02/10English95
Evidence for Covalent DNA Adduction by Ochratoxin A following Chronic Exposure to Rat and Subacute Exposure to Pig2004/08/28English95
Metabolites in Safety Testing (MIST): Considerations of Mechanisms of Toxicity with Dose, Abundance, and Duration of Treatment2009/01/23English94
Predicting Hepatotoxicity Using ToxCast in Vitro Bioactivity and Chemical Structure2015/03/09English94
Acetaldehyde in Mainstream Tobacco Smoke:  Formation and Occurrence in Smoke and Bioavailability in the Smoker2002/11/01English94