| Computer-based de novo design of drug-like molecules | 2005/08/01 | English | 533 |
| Multicomponent therapeutics for networked systems | 2005/01/01 | English | 533 |
| mRNA vaccines for infectious diseases: principles, delivery and clinical translation | 2021/08/25 | English | 531 |
| Polymer–drug conjugate therapeutics: advances, insights and prospects | 2018/12/12 | English | 530 |
| Vemurafenib: the first drug approved for BRAF-mutant cancer | 2012/10/12 | English | 526 |
| Therapeutic potential of venom peptides | 2003/10/01 | English | 526 |
| Mining the Wnt pathway for cancer therapeutics | 2006/12/01 | English | 524 |
| NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential | 2006/09/01 | English | 522 |
| Molecular imaging in drug discovery and development | 2003/02/01 | English | 522 |
| Subcellular targeting strategies for drug design and delivery | 2010/01/01 | English | 522 |
| Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy | 2010/08/01 | English | 519 |
| Antibody targeted drugs as cancer therapeutics | 2006/01/20 | English | 517 |
| Antiviral agents active against influenza A viruses | 2006/12/01 | English | 516 |
| Therapeutic application of histone deacetylase inhibitors for central nervous system disorders | 2008/10/01 | English | 514 |
| Targeting inflammation in the treatment of type 2 diabetes: time to start | 2014/05/23 | English | 513 |
| Metabolic targets for cancer therapy | 2013/10/11 | English | 510 |
| Tamoxifen: a most unlikely pioneering medicine | 2003/03/01 | English | 509 |
| Protein tyrosine phosphatase 1B inhibitors for diabetes | 2002/09/01 | English | 508 |
| Acyclic nucleoside phosphonates: a key class of antiviral drugs | 2005/11/01 | English | 507 |
| Antimalarial drug discovery: efficacy models for compound screening | 2004/06/01 | English | 507 |
| G protein-coupled receptors: novel targets for drug discovery in cancer | 2010/12/31 | English | 506 |
| Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system | 2009/09/01 | English | 506 |
| The war against influenza: discovery and development of sialidase inhibitors | 2007/12/01 | English | 505 |
| RAS-targeted therapies: is the undruggable drugged? | 2020/06/11 | English | 503 |
| GLIA: A novel drug discovery target for clinical pain | 2003/12/01 | English | 503 |
| The secret ally: immunostimulation by anticancer drugs | 2012/02/03 | English | 502 |
| Next generation antibody drugs: pursuit of the 'high-hanging fruit' | 2017/12/01 | English | 499 |
| The antifungal pipeline: a reality check | 2017/05/12 | English | 499 |
| Integrase inhibitors to treat HIV/Aids | 2005/02/24 | English | 497 |
| Telomere maintenance as a target for anticancer drug discovery | 2002/05/01 | English | 497 |