| Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases | 2012/08/01 | English | 1,248 |
| The resurgence of covalent drugs | 2011/04/01 | English | 1,225 |
| Lab-on-a-chip: microfluidics in drug discovery | 2006/03/01 | English | 1,221 |
| The therapeutic potential of carbon monoxide | 2010/09/01 | English | 1,219 |
| Targeting mitochondria for cancer therapy | 2010/05/14 | English | 1,212 |
| PI3K and cancer: lessons, challenges and opportunities | 2014/01/31 | English | 1,205 |
| Glycans in cancer and inflammation — potential for therapeutics and diagnostics | 2005/06/01 | English | 1,200 |
| Interfering with pH regulation in tumours as a therapeutic strategy | 2011/09/16 | English | 1,195 |
| Aptamers as targeted therapeutics: current potential and challenges | 2016/11/03 | English | 1,191 |
| Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets | 2008/06/01 | English | 1,163 |
| ADMET in silico modelling: towards prediction paradise? | 2003/03/01 | English | 1,152 |
| How were new medicines discovered? | 2011/06/24 | English | 1,152 |
| Diagnosing the decline in pharmaceutical R&D efficiency | 2012/03/01 | English | 1,150 |
| Small-molecule inhibitors of protein–protein interactions: progressing towards the dream | 2004/04/01 | English | 1,147 |
| Adeno-associated virus vector as a platform for gene therapy delivery | 2019/02/01 | English | 1,143 |
| Targeting macrophages: therapeutic approaches in cancer | 2018/10/26 | English | 1,136 |
| Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies | 2014/08/08 | English | 1,136 |
| The history and future of targeting cyclin-dependent kinases in cancer therapy | 2015/01/30 | English | 1,135 |
| Coronaviruses — drug discovery and therapeutic options | 2016/02/12 | English | 1,135 |
| Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases | 2011/06/01 | English | 1,133 |
| Believe it or not: how much can we rely on published data on potential drug targets? | 2011/08/31 | English | 1,131 |
| Histone-deacetylase inhibitors: novel drugs for the treatment of cancer | 2002/04/01 | English | 1,109 |
| Therapeutic options for the 2019 novel coronavirus (2019-nCoV) | 2020/02/10 | English | 1,106 |
| Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders | 2014/08/18 | English | 1,094 |
| Autophagy modulation as a potential therapeutic target for diverse diseases | 2012/08/31 | English | 1,092 |
| Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery | 2014/10/07 | English | 1,084 |
| Targeting microRNAs in cancer: rationale, strategies and challenges | 2010/10/01 | English | 1,078 |
| Applications of machine learning in drug discovery and development | 2019/04/11 | English | 1,069 |
| Prodrugs: design and clinical applications | 2008/03/01 | English | 1,062 |
| Targeting cancer metabolism: a therapeutic window opens | 2011/08/31 | English | 1,049 |