Drug Design, Development and Therapy

Title Publication Date Language Citations
Preliminary in vitro and in vivo assessment of a new targeted inhibitor for choroidal neovascularization in age-related macular degeneration2016/10/01English
Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date2016/09/01English
Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells2016/09/01English
Efficacy of an acquainted drug in the treatment of inflammatory low back pain: sulfasalazine under investigation2016/09/01English
Early intervention of long-acting nifedipine GITS reduces brachial–ankle pulse wave velocity and improves arterial stiffness in Chinese patients with mild hypertension: a 24-week, single-arm, open-label, prospective study2016/10/01English
Ustekinumab in treatment of Crohn’s disease: design, development, and potential place in therapy2016/11/01English
Comment on the case report “Possible association between acetazolamide administration during pregnancy and multiple congenital malformations”2016/11/01English
Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling [Retraction]2023/04/01English
Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects2023/04/01English
Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell Polarization2023/04/01English
Pharmacokinetic Interactions Between Bazedoxifene and Cholecalciferol: An Open-Label, Randomized, Crossover Study in Healthy Male Volunteers2023/04/01English
Tuo-Min-Ding-Chuan Decoction Alleviates Airway Inflammations in the Allergic Asthmatic Mice Model by Regulating TLR4-NLRP3 Pathway-Mediated Pyroptosis: A Network Pharmacology and Experimental Verification Study2023/06/01English
Dexmedetomidine Improved Sleep Quality in the Intensive Care Unit After Laryngectomy2023/06/01English
Feasibility and Safety of Remazolam versus Propofol When Inserting Laryngeal Masks Without Muscle Relaxants During Hysteroscopy2023/05/01English
The Application of Dupilumab to Pediatric Patients Aged 6–11yrs with Moderate-to-Severe Atopic Dermatitis Whose Disease is Not Adequately Controlled: The Clinical Data so Far2023/05/01English
Knowledge Mapping of Drug Repositioning’s Theme and Development2023/04/01English
Thoughtful Discussion on Article “Antimicrobial Peptide Cec4 Eradicates Multidrug-Resistant Acinetobacter baumannii in vitro and in vivo” [Letter]2023/05/01English
Nano-Emulsion Based Gel for Topical Delivery of an Anti-Inflammatory Drug: In vitro and in vivo Evaluation2023/05/01English
AS-605240 Blunts Osteoporosis by Inhibition of Bone Resorption2023/04/01English
Clinical Utility of Osilodrostat in Cushing’s Disease: Review of Currently Available Literature2023/04/01English
Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis2023/04/01English
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease2023/05/01English
Effects of Empagliflozin on Gut Microbiota in Heart Failure with a Preserved Ejection Fraction: The Design of a Pragmatic Randomized, Open-Label Controlled Trial (EMPAGUM)2023/05/01English
Qifu Yixin Formula Improves Heart Failure by Enhancing β-Arrestin2 Mediated the SUMOylation of SERCA2a2024/03/01English
Mechanisms of Action of Potentilla discolor Bunge in Type 2 Diabetes Mellitus Based on Network Pharmacology and Experimental Verification in Drosophila2024/03/01English
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling2024/03/01English
Exploration of the in vitro Antiviral Effects and the Active Components of Changyanning Tablets Against Enterovirus 712024/03/01English
A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles2024/02/01English
Bibliometric and Visualization Analysis of Stem Cell Therapy for Erectile Dysfunction2024/03/01English
Randomized Double-Blinded Comparison of Intermittent Boluses Phenylephrine and Norepinephrine for the Treatment of Postspinal Hypotension in Patients with Severe Pre-Eclampsia During Cesarean Section2024/02/01English