Drug Design, Development and Therapy

Title Publication Date Language Citations
MicroRNA-125a-5p modulates human cervical carcinoma proliferation and migration by targeting ABL22015/12/01English
Cost-effectiveness comparison of lamivudine plus adefovir combination treatment and nucleos(t)ide analog monotherapies in Chinese chronic hepatitis B patients2016/03/01English
Spotlight on lenvatinib in the treatment of thyroid cancer: patient selection and perspectives2016/02/01English
Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers2016/01/01English
5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors2016/02/01English
Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine2016/02/01English
Formulation, optimization, and pharmacodynamic evaluation of chitosan/phospholipid/β-cyclodextrin microspheres2016/01/01English
Short-term maraviroc exposure, a clinical approach to decide on maraviroc prescription in HIV-1-infected treatment-naïve patients2016/01/01English
High-dose OxyContin to treat pain associated with bone metastasis in patients with small-cell lung cancer: a case study report2016/01/01English
Treatment of osteoporosis with eldecalcitol, a new vitamin D analog: a comprehensive review and meta-analysis of randomized clinical trials [Corrigendum]2016/02/01English
Dose comparison of conivaptan (Vaprisol®) in patients with euvolemic or hypervolemic hyponatremia – efficacy, safety, and pharmacokinetics2016/01/01English
Effects of Dang-Gui-Bu-Xue-Tang, an herbal decoction, on iron uptake in iron-deficient anemia2016/03/01English
A 5-fluorouracil-loaded floating gastroretentive hollow microsphere: development, pharmacokinetic in rabbits, and biodistribution in tumor-bearing mice2016/03/01English
In vitro stress effect on degradation and drug release behaviors of basic fibroblast growth factor – poly(lactic-co-glycolic-acid) microsphere2016/01/01English
Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation2016/02/01English
The clinicopathological significance and ethnic difference of FHIT hypermethylation in non-small-cell lung carcinoma: a meta-analysis and literature review2016/02/01English
Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones reduce oxidative damage in ultraviolet B-irradiated HaCaT cells via a p38MAPK-independent mechanism2016/01/01English
Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations2017/09/01English
Alginate oligosaccharide indirectly affects toll-like receptor signaling via the inhibition of microRNA-29b in aneurysm patients after endovascular aortic repair2017/09/01English
Puerarin transport across rat nasal epithelial cells and the influence of compatibility with paeoniflorin and menthol2017/09/01English
Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H:quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials2017/11/01English
Downregulation of A20 increases the cytotoxicity of IFN-γ in hepatocellular carcinoma cells2017/09/01English
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome2017/09/01English
Failure mode and effects analysis drastically reduced potential risks in clinical trial conduct2017/10/01English
Novel production method of innovative antiangiogenic and antitumor small peptides in <em>Escherichia coli</em>2017/11/01English
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway2017/11/01English
Quantum mechanics implementation in drug-design workflows: does it really help? [Corrigendum]2017/11/01English
Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-&kappa;B decoy oligodeoxynucleotides2017/10/01English
Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects2016/04/01English
Per-residue energy decomposition pharmacophore model to enhance virtual screening in drug discovery: a study for identification of reverse transcriptase inhibitors as potential anti-HIV agents2016/04/01English