Clinical Pharmacology & Therapeutics

Title Publication Date Language Citations
A method for estimating the probability of adverse drug reactions1981/08/017,586
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework2001/03/01English3,850
Nanoparticles in Medicine: Therapeutic Applications and Developments2007/10/241,586
A physiological approach to hepatic drug clearance1975/10/01English1,277
Pharmacogenomics Knowledge for Personalized Medicine2012/10/011,176
Clinical biostatistics: LIV. The biostatistics of concordance1981/01/01794
Monoclonal Antibody Pharmacokinetics and Pharmacodynamics2008/09/10699
Pharmacogenetics: From Bench to Byte— An Update of Guidelines2011/03/16692
Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d‐tubocurarine1979/03/01English689
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network2011/01/26681
Identification of functionally variant MDR1 alleles among European Americans and African Americans2001/08/01English678
Case Definition and Phenotype Standardization in Drug-Induced Liver Injury2011/05/04675
Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man1971/03/01English659
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors2015/06/29English627
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update2013/05/22626
Development of a Large-Scale De-Identified DNA Biobank to Enable Personalized Medicine2008/05/21606
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance2004/01/01English604
Minimization: A new method of assigning patients to treatment and control groups1974/05/01English570
Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin2008/02/27561
Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer2010/03/31554
Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance2006/12/01English546
The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype2007/10/31538
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects2001/03/01English521
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants2006/01/01English510
I-SPY 2: An Adaptive Breast Cancer Trial Design in the Setting of Neoadjuvant Chemotherapy2009/05/13505
Changes in plasma protein binding have little clinical relevance2002/03/01English505
Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs2010/02/03492
Clinical pharmacology of buprenorphine: Ceiling effects at high doses1994/05/01490
Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor2005/10/01English464
Pharmacologic effects of CI‐581, a new dissociative anesthetic, in man1965/05/01English448