Molecular Pharmaceutics

Title Publication Date Language Citations
druGAN: An Advanced Generative Adversarial Autoencoder Model for de Novo Generation of New Molecules with Desired Molecular Properties in Silico2017/08/04English295
An Overview of Pharmaceutical Cocrystals as Intellectual Property2007/05/04English291
Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms2008/03/21English291
Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data2016/06/08English287
Overcoming Nonviral Gene Delivery Barriers: Perspective and Future2013/10/16English287
Coamorphous Drug Systems: Enhanced Physical Stability and Dissolution Rate of Indomethacin and Naproxen2011/08/15English286
Mechanisms of Nanoparticle Internalization and Transport Across an Intestinal Epithelial Cell Model: Effect of Size and Surface Charge2014/10/30English279
Subdomain IB Is the Third Major Drug Binding Region of Human Serum Albumin: Toward the Three-Sites Model2013/03/26English278
Screening for Pharmaceutical Cocrystal Hydrates via Neat and Liquid-Assisted Grinding2007/05/12English269
Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels2011/07/08English265
Radiolabeled Multimeric Cyclic RGD Peptides as Integrin αvβ3Targeted Radiotracers for Tumor Imaging2006/07/21English261
Solid State Amorphization of Pharmaceuticals2008/10/28English260
Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery2015/09/23English254
The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles2010/05/26English251
Indocyanine Green-Containing Nanostructure as Near Infrared Dual-Functional Targeting Probes for Optical Imaging and Photothermal Therapy2011/01/14English250
Nanotheranostics and Image-Guided Drug Delivery: Current Concepts and Future Directions2010/10/06English247
Enhanced Antiproliferative Activity of Transferrin-Conjugated Paclitaxel-Loaded Nanoparticles Is Mediated via Sustained Intracellular Drug Retention2005/06/21English246
Endocytosis and Intracellular Trafficking as Gateways for Nanomedicine Delivery: Opportunities and Challenges2012/08/20English244
Reaction Crystallization of Pharmaceutical Molecular Complexes2006/03/14English241
Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear Trafficking2010/10/27English241
Shrinkage of a Rapidly Growing Tumor by Drug-Loaded Polymersomes:  pH-Triggered Release through Copolymer Degradation2006/03/18English240
Methotrexate Conjugated to Gold Nanoparticles Inhibits Tumor Growth in a Syngeneic Lung Tumor Model2007/08/21English233
RGD-Conjugated Dendrimer-Modified Gold Nanorods for in Vivo Tumor Targeting and Photothermal Therapy2009/11/16English231
Drug-Loaded Carbon Nanohorns:  Adsorption and Release of Dexamethasone in Vitro2004/09/24English230
Nanoparticle Characterization: State of the Art, Challenges, and Emerging Technologies2013/03/21English227
Flexible Filaments for in Vivo Imaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage2009/03/25English227
Dendrimers as Drugs:  Discovery and Preclinical and Clinical Development of Dendrimer-Based Microbicides for HIV and STI Prevention2005/06/22English224
Role of Nuclear Receptors in the Adaptive Response to Bile Acids and Cholestasis:  Pathogenetic and Therapeutic Considerations2006/05/19English223
3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs2008/08/05English221
Cocrystals of Hydrochlorothiazide: Solubility and Diffusion/Permeability Enhancements through Drug–Coformer Interactions2015/04/02English215