Journal of Medicinal Chemistry

Title Publication Date Language Citations
Artificial Intelligence-Assisted Optimization of Antipigmentation Tyrosinase Inhibitors: De Novo Molecular Generation Based on a Low Activity Lead Compound2024/04/23English
Discovery of Novel Dual Inhibitors Targeting Mutant IDH1 and NAMPT for the Treatment of Glioma with IDH1Mutation2024/04/23English
Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity2024/04/22English
Design, Synthesis, and Biological Evaluation of β-Trifluoroethoxydimethyl Selenides as Potent Antiosteoporosis Agents2024/04/17English
Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors2024/04/17English
Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer2024/04/17English
Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs2024/04/13English
Structure-Guided Discovery and Preclinical Assessment of Novel (Thiophen-3-yl)aminopyrimidine Derivatives as Potent ERK1/2 Inhibitors2024/04/13English
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy2024/04/13English
Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity2024/04/15English
Targeting KRAS Diversity: Covalent Modulation of G12X and Beyond in Cancer Therapy2024/04/15English
Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3′-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury2024/04/15English
FETPY: a Diiron(I) Thio–Carbyne Complex with Prominent Anticancer Activity In Vitro and In Vivo2024/04/19English
Lead Optimization of Butyrolactone I as an Orally Bioavailable Antiallergic Agent Targeting FcγRIIB2024/04/19English
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo2024/04/18English
Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles2024/04/20English
Correction to “Development of Cytotoxic GW7604-Zeise’s Salt Conjugates as Multitarget Compounds with Selectivity for Estrogen Receptor-Positive Tumor Cells”2024/04/23English
Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease2024/04/22English
Design of Evodiamine–Glucose Conjugates with Improved In Vivo Antitumor Activity2024/04/22English
Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect2024/04/22English
Discovery and Structure–Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists2024/04/22English
Mitochondria-Selective Dicationic Small-Molecule Ligand Targeting G-Quadruplex Structures for Human Colorectal Cancer Therapy2024/04/16English
Synthesis and Structure–Activity Relationships for Glutamate Transporter Allosteric Modulators2024/04/16English
1996/01/01English
Analytical Chemistry in a GMP Environment:  A Practical Guide Edited by James M. Miller and Jonathan B. Crowther. John Wiley & Sons, Inc., New York. 2000. xxiv + 488 pp. 16 × 24 cm. ISBN 0-471-31431-5. $115.00.2001/09/19English
Metal Ions in Biological Systems. Volume 38. Probing of Proteins by Metal Ions and Their Low Molecular Weight Complexes Edited by Astrid Sigel and Helmut Sigel. Marcel Dekker, New York. 2001. xlvii + 690 pp. 16 × 23.5 cm. ISBN 0-8247-0289-1. $250.00.2001/10/11English
CRC Handbook of Laboratory Safety. 5th Edition By A. Keith Furr. CRC Press, Boca Raton, FL. 2000. xvii + 774 pp. 18 × 26 cm. ISBN 0-8493-2523-4. $149.99.2001/01/30English
Biodiversity. New Leads for the Pharmaceutical and Agrochemical Industries Edited by Stephen K. Wrigley, Martin A. Hayes, Robert Thomas, Ewan J. T. Chrystal, and Neville Nicholson. The Royal Society of Chemistry, Cambridge, U.K. 2000. vi + 314 pp. 16 × 24 cm. ISBN 0-85404-830-8. £59.50.2001/01/16English
How To Find Chemical Information:  A Guide for Practicing Chemists, Educators, and Students, 3rd Edition By Robert E. Maizell. John Wiley & Sons, Inc., New York. 1998. xxiii + 515 pp. 16 × 23 cm. ISBN 0-471-125792. $64.95.1998/12/22English
Organic Reactions. Volume 53 Leo A. Paquette, Editor-in-Chief. John Wiley & Sons, Inc., New York. 1998. vii + 654 pp. 16 x 24 cm. ISBN 0-471-32609-7. $95.00.1999/05/25English