Bioconjugate Chemistry

Title Publication Date Language Citations
Toxicity of Gold Nanoparticles Functionalized with Cationic and Anionic Side Chains2004/06/05English1,083
Theranostics: Combining Imaging and Therapy2011/08/29English885
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture1993/09/01English802
Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects2010/04/16English732
Noninvasive Imaging of Quantum Dots in Mice2003/12/30English712
Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?2016/09/02English652
High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates1999/02/26English644
Cyanine dye labeling reagents: Sulfoindocyanine succinimidyl esters1993/03/01English640
68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging2012/03/13English635
Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging2008/11/21English626
Mechanism of Amide Formation by Carbodiimide for Bioconjugation in Aqueous Media1995/01/01English563
Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property:  Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy2004/12/22English562
In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers1996/01/01English556
Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells:  Nanoscale Hole Formation and Enhanced Membrane Permeability2006/05/01English536
Synthesis of Polyamidoamine Dendrimers Having Poly(ethylene glycol) Grafts and Their Ability To Encapsulate Anticancer Drugs2000/11/01English492
Interaction of Poly(amidoamine) Dendrimers with Supported Lipid Bilayers and Cells:  Hole Formation and the Relation to Transport2004/06/22English471
pH-Responsive Copolymer Assemblies for Controlled Release of Doxorubicin2005/02/11English449
Antibody−Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies2009/09/21English441
Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C2001/02/16English439
Polyethylenimine-graft-Poly(ethylene glycol) Copolymers:  Influence of Copolymer Block Structure on DNA Complexation and Biological Activities as Gene Delivery System2002/06/22English427
Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development2015/01/30English421
A brief survey of methods for preparing protein conjugates with dyes, haptens and crosslinking reagents1992/01/01English403
Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo1992/09/01English397
Electrochemistry of Methylene Blue Bound to a DNA-Modified Electrode1997/01/01English393
The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery2018/11/19English380
The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry2011/05/18English368
Gemtuzumab Ozogamicin, A Potent and Selective Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia2001/12/19English368
“SMART” Drug Delivery Systems:  Double-Targeted pH-Responsive Pharmaceutical Nanocarriers2006/06/30English368
Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery:  Effects of Linker Technology on Efficacy and Toxicity2005/12/22English359
Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity2008/06/14English358