Drug Metabolism and Pharmacokinetics

Title Publication Date Language Citations
Metabolic Activation of Carcinogenic Arylhydroxamic Acid by Liver Microsomal Carboxylesterase1993/01/01English
ポピュレーションファーマコキネティクスの動物実験への応用1997/01/01English
Absorption, distribution and excretion of L-DOPS in animals.1987/01/01English
薬物代謝酵素ｐ４５０の基質特異性予測2000/01/01English
2-iodobenzyl系化合物の脳内取り込みに及ぼす修飾基の影響　(1) 主環側の生体内動態1986/01/01English
Placental transfer and milk transfer of 14C-benidipineHCl.1990/01/01English
ステロイド硫酸転移酵素の下垂体ホルモンによる調節1988/01/01English
Species differences in the substrate specificity of carboxylesterase isozymes in mammals and humans1998/01/01English
Sufficient pharmacokinetic and disposition studies using experimental animals are by all means necessary1998/01/01English
ベプチドの三重水素化およびその代謝研究1988/01/01English
ヒスタミン<I>N</I>-メチルトランスフェラーゼの遺伝多型1998/01/01English
OCULAR MEMBRANE PERMEABILITY AND ABSORPTION OF DRUG1997/01/01English
The new development of the mechanism of CYP2B induction.1999/01/01English
Studies on the Metabolic Fate of Flecainide Acetate. (1). Blood Levels, Distribution, Metabolism and Excretion in Rats after Repeated Intravenous Administration.1999/01/01English
Metabolic Fate of (.+-.)-2-((2-(isobutylmethylamino)benzyl)sulfinyl)-1H-benzimidazole (NC-1300-O-3). (2): Absorption, Distribution and Excretion after Consecutive Oral Administration, and Transfer into Fetus and Milk in Rats.1994/01/01English
EFFECT OF MEMBRANE SURFACE POTENTIAL ON THE PERMEATION OF IONIC DRUGS THROUGH THE INTESTINAL BRUSH-BORDER MEMBRANE1994/01/01English
PHENOBARBITAL-INDUCIBLE GUINEA PIG CYTOCHROMES P450: ISOZYMES AND THE GENE STRUCTURE1997/01/01English
Studies on the metabolic fate of Benazepril hydrochloride in rats I: Plasma level profile, distribution, metabolism and excretion after single administration.1992/01/01English
インドメタシンの経皮吸収に対するレシチンの効果1986/01/01English
放射性標識体を用いたインビボ試験1991/01/01English
Multiplicity and Species Differences of Carboxylesterase Isozymes in Mammals and Humans.1998/01/01English
Metabolic Fate of a Novel Antiulcer Agent, T-593. (III). Blood Concentration, Distribution, Metabolism, Excretion and Effects on Hepatic Drug Metabolizing Enzyme System after Repeated Oral Administration to Rats.1998/01/01English
Tobramycin腎移行過程のモーメント解析1989/01/01English
Physiological and Anatomical Factors Affecting Intestinal Drug Absorption and Absorption Enhancement by Modifying Their Factors.1992/01/01English
Physiological Mechanism-Based Evaluation of Nonlinear Gastrointestinal Absorption in Rats: <I>In Vitro-In Vivo</I> Correlation and Prediction of Drug Absorption1997/01/01English
Enatiomer separation of dihydropyridine derivative calcium antagonists by high-performance liquid chromatography using modified Pirkle-type chiral stationary phases and the effect of grapefruit juice on the pharmacokinetics of dihydropyridine enantiomers.1998/01/01English
Disposition of Marograstim (KW-2228) (5) : Correlation between bioassay and ELISA in measurement for plasma concentration of KW-2228 after intravenous or subcutaneous administration of KW-22281992/01/01English
Hepatic Uptake Mechanisms for Pravastatin and Temocaprilat.1998/01/01English
CHRACTERIZATION OF CYTOCHROME P4502D6 VARIANTS EXPRESSED IN YEAST CELLS2000/01/01English
The circumstances of present guidelines for nonclinical pharmacokinetic studies from establishment to revision1996/01/01English