Genes to Cells

Title Publication Date Language Citations
Novel translocation intermediate allows re‐evaluation of roles of ATP, proton motive force and SecG at the late stage of preprotein translocation2016/11/04English
In the most popular type of next‐generation DNA sequencer, DNA fragments are PCR‐amplified in the slide's channel coated by a lawn of PCR primers to form myriads of clone DNA clusters. After that, the DNA sequence of each cluster is determined by taking photographs of fl uorescent signals on the slide with the image sensor again and again after each single‐nucleotide extension step of a novel dye‐terminator method. Thus, the reaction proceeding in the next‐generation sequencer is massively parallel sequencing. In this drawing, we schematically expressed this mechanism with a flying hawk (image sensor) viewing clusters of pine trees (DNA) on the channel‐shaped reclaimed land divided by embankments. Designed by TRAIS Co., Ltd. (Kobe, Japan)2016/02/01English
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Yeasts for Global Happiness: report of the 14th International Congress on Yeasts (ICY14) held in Awaji Island2017/01/20English
Issue Information2016/12/01English
Volume Contents2016/12/01English
Index2016/12/01English
Shoki (Zhong Kui in Chinese), derived from Chinese Taoism, is a god for warding off diseases. According to a legend, one night when Emperor Genso (Xuanzong) of the Tang Dynasty had a high fever, Shoki appeared to him in a dream, killed a monster, and saved the Emperor at last. In tribute to the legend, Shoki has been worshipped as a god who protects people from illness for hundreds of years in China and Japan. The role of Shoki in the legend is that of the immune system itself. In this drawing, Shoki holds asasumata (spear fork) with an IgG‐like spearhead in the right hand and wears a cloth with a crest of IgM and a pattern of a dendritic cell; they are weapons of mammalian adaptive immunity. In contrast, his left hand contains a monster (pathogen) by melanization, which is one of the weapons of the innate immunity of insects. We thank Prof. Hirotaka Kanuka's lab (The Jikei University School of Medicine) for their valuable suggestions for our drawing. Designed by TRAIS Co., Ltd. (Kobe, Japan)2015/09/01English
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FRET (Fluorescence Resonance Energy Transfer), which is a phenomenon of energy transfer between two adjacent fluorescent molecules, has been applied to visualization of interaction between proteins in living cells and so on. To carry out high‐efficiency FRET, not only the distance between two molecules must be very close (less than about 10 nm) but the relative orientation of two chromophores must also be optimized. One of the women in this picture carries the other with attention paid on how they are oriented to each other, and successfully lightens the plum blossoms just like FRET. Designed by TRAIS Co., Ltd. (Kobe, Japan)2014/02/24English
It was in 1936 when the existence of ‘florigen’ was initially predicted as a plant hormone that transmits information on daylight length at their leaves to the tip of the stem and stimulates flower initiation. In 2007, it was finally identified as a protein, which is coded by the FT gene in Arabidopsis thaliana. FT protein is produced in the leaves and transmitted to the growing tip at the shoot apical meristem via the phloem, and interacts with a transcription factor (the product of the FD gene in Arabidopsis) to induce genes involved in flower initiation. In this drawing, an actor performing FT is contacting another actor performing FD, and trying to stimulate flower initiation with him in front of hydrangea flowers that represent the month of June in Japan. Designed by TRAIS Co., Ltd. (Kobe, Japan)2015/06/01English
An atmospheric ghost light that is called Kitsunebi (‘fox light’) is described in Japanese folklore. The most famous one is the one in the Oji Inari shrine (Kita‐ku, Tokyo). Every New Year's Eve in the old lunar calendar, foxes from all of the Kanto area, all suited up, gather to this shrine, light Kitsunebi under a big tree, and then stand in line. In this drawing, while the line of Kitsunebi in a standard single color is ahead of the rest, the rest of the foxes gathering under the tree are holding up ‘new generation Kitsunebi‘ in various colors and about to join the line. This scene is reminiscent of the green fluorescent protein (GFP; here are three spatial structure models) genetically engineered so as to be available in different emission peaks. Designed by TRAIS Co., Ltd. (Kobe, Japan)2015/01/28English
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Enhancer and silencer binding proteins involved in the rat cdc2 promoter activation at the G1/S boundary1999/04/01English
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In memory of Jun‐ichi Tomizawa, Professor Emeritus of the National Institute of Genetics2018/07/01English
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Evolutionary origin of the type 2 corticotropin‐releasing hormone receptor γ splice variant2019/03/03English
Human Ebp1 rescues the synthetic lethal growth of fission yeast cells lacking Cdb4 and Nup1842020/03/01English
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YoungMito 2018: Report on the 1st International Mitochondria Meeting for Young Scientists2018/10/01English
Differential regulation of p27Kip1 depending on culture conditions and its correlation with status of p14ARF and p532022/01/17English
Issue Information2022/01/01English