Molecular Neurodegeneration

Title Publication Date Language Citations
Adult hippocampal neurogenesis and its role in Alzheimer's disease2011/01/01English668
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease2014/01/01English364
The Alzheimer's disease Beta-secretase enzyme, BACE12007/01/01330
Alzheimer's disease: synaptic dysfunction and Aβ2009/01/01English327
The role of tau in neurodegeneration2009/01/01English297
Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation2013/01/01English247
α-Synuclein and neuronal cell death2009/01/01English244
Regulated protein aggregation: stress granules and neurodegeneration2012/01/01English237
Calcium signaling in neurodegeneration2009/01/01English218
Biology and pathophysiology of the amyloid precursor protein2011/01/01English210
Tau exon 10 alternative splicing and tauopathies2008/01/01English192
SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease2014/01/01English183
Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons2011/01/01English172
Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease2012/01/01English159
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway2012/01/01English151
The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease2008/01/01English146
Immunotherapy for Alzheimer’s disease: hoops and hurdles2013/01/01English131
Fluid biomarkers in Alzheimer’s disease – current concepts2013/01/01English130
All-you-can-eat: autophagy in neurodegeneration and neuroprotection2009/01/01English126
Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease2014/01/01English116
BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease2012/01/01English109
Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death2014/01/01English109
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model2010/01/01English109
Modeling Alzheimer’s disease in transgenic rats2013/01/01English107
Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain2011/01/01English106
Spinal cord trauma and the molecular point of no return2012/01/01English96
Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics2014/01/01English94
Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease2010/01/01English93
In vivo silencing of alpha-synuclein using naked siRNA2008/01/01English92
The gene coding for PGC-1α modifies age at onset in Huntington's Disease2009/01/01English91