Pharmaceutical Bioprocessing

Title Publication Date Language Citations
On the way to commercializing plant cell culture platform for biopharmaceuticals: present status and prospect2014/12/01English67
Production and purification of the multifunctional enzyme horseradish peroxidase2013/08/01English45
Computational fluid dynamics as a modern tool for engineering characterization of bioreactors2014/02/01English41
Viral clearance for biopharmaceutical downstream processes2015/04/01English34
Developability assessment as an early de-risking tool for biopharmaceutical development2013/04/01English33
Application of spectroscopic methods for monitoring of bioprocesses and the implications for the manufacture of biologics2014/06/01English32
Multimodal chromatography: debottlenecking the downstream processing of monoclonal antibodies2015/06/01English32
Biopharmaceutical protein production bySaccharomyces cerevisiae: current state and future prospects2014/04/01English31
Emerging technologies for the integration and intensification of downstream bioprocesses2013/12/01English30
The impact of continuous multicolumn chromatography on biomanufacturing efficiency2013/10/01English30
Generation of monoclonal antibody-producing mammalian cell lines2013/04/01English28
The use of glutamine synthetase as a selection marker: recent advances in Chinese hamster ovary cell line generation processes2013/12/01English25
Manufacturing of viral vectors for gene therapy: part I. Upstream processing2014/04/01English23
Manufacturing of viral vectors: part II. Downstream processing and safety aspects2014/06/01English21
Role of Chinese hamster ovary central carbon metabolism in controlling the quality of secreted biotherapeutic proteins2014/02/01English21
Virus clearance methods applied in bioprocessing operations: an overview of selected inactivation and removal methods2014/02/01English21
The impact of process temperature on mammalian cell lines and the implications for the production of recombinant proteins in CHO cells2014/02/01English20
The hidden potential of small synthetic molecules and peptides as affinity ligands for bioseparations2013/12/01English20
Quality by design for biopharmaceuticals: a historical review and guide for implementation2013/04/01English18
Identifying and eliminating cell culture process variability2014/12/01English18
Modification and qualification of a stirred single-use bioreactor for the improved expansion of human mesenchymal stem cells at benchtop scale2014/08/01English17
Applying quality by design to glycoprotein therapeutics: experimental and computational efforts of process control2013/04/01English16
In situmicroscopy and MIR-spectroscopy as non-invasive optical sensors for cell cultivation process monitoring2014/04/01English15
3D scaffolds in tissue engineering and regenerative medicine: beyond structural templates?2013/08/01English15
The use ofDrosophilaS2 cells in R&D and bioprocessing2013/06/01English15
Toward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectives2014/10/01English13
Cell therapies: why scale matters2015/04/01English13
Improving the downstream processing of vaccine and gene therapy vectors with continuous chromatography2015/12/01English13
High expression of the aspartate–glutamate carrier Aralar1 favors lactate consumption in CHO cell culture2013/04/01English12
Automated disposable small-scale bioreactor for high-throughput process development: implementation of the 24 bioreactor array2015/06/01English12