Perspectives in Drug Discovery and Design

Title Publication Date Language Citations
Non-nucleoside inhibitors of HIV-1 reverse transcriptase1993/08/01English
The role of metalloproteinases and their inhibitors in regulating mammary epithelial morphology and function in vivo1995/07/01English
Binary encoded small-molecule libraries in drug discovery and optimization1995/04/01English
Biologically displayed random peptides as reagents in mapping protein-protein interactions1995/04/01English
AIDS — The challenge1993/08/01English
Interleukin-1β-converting enzyme and related proteases as potential targets in inflammation and apoptosis1995/07/01English
Supercomputing and drug discovery research1993/12/01English
Inhibitory effects of HIV-1 gp120 on myelin formation1996/12/01English
Crystal structures of HIV-1 protease-inhibitor complexes1993/08/01English
The chirality problem in P-substituted oligonucleotides1996/12/01English
New approaches to QSAR: Neural networks and machine learning1993/12/01English
Ecotin: A most adaptable protease inhibitor1995/07/01English
A good ligand is hard to find: Automated docking methods1993/12/01English
Structural aspects of the serpin reaction coordinate1995/07/01English
Computer-aided drug discovery and design1993/12/01English
The HIV gp120-CD4 interaction: A target for pharmacological or immunological intervention?1993/08/01English
Specificity of antisense oligonucleotides1996/12/01English
Hirudin and Hirulog: Advances in antithrombotic therapy1994/04/01English
Toward a more efficient handling of conformational flexibility in computer-assisted modelling of drug molecules1995/12/01English
Immunosuppressive therapy: Current limitations and future prospects1994/08/01English
Sperm as mitogenic cofactors for HIV transmission1996/12/01English
The specificity of the HIV-1 protease1993/08/01English
The hyperglycosylation of HIV envelope: An opportunity to alter virus infectivity?1996/12/01English
The immunophilins1994/08/01English
Automated chemical hypothesis generation and database searching with Catalyst®1995/12/01English
Review of HIV-1 reverse transcriptase three-dimensional structure: Implications for drug design1993/08/01English
Cysteine proteases and tumor progression1995/07/01English
Iminosugar glycosylation inhibitors as anti-HIV agents1993/08/01English
Structural studies on FK-506, cyclosporin A and their immunophilin complexes1994/08/01English
Matrix metalloproteases: Structure-based drug discovery targets1995/07/01English