| Mechanisms of Disease: is osteoporosis the obesity of bone? | 2006/01/01 | English | 668 |
| Interleukin 6: from bench to bedside | 2006/11/01 | English | 452 |
| Adipokines as emerging mediators of immune response and inflammation | 2007/12/01 | English | 377 |
| Genomic and nongenomic effects of glucocorticoids | 2008/09/02 | English | 366 |
| Control of autoimmune diseases by the vitamin D endocrine system | 2008/07/01 | English | 361 |
| Tendinopathy—from basic science to treatment | 2008/02/01 | English | 309 |
| Mechanisms of Disease: a 'DAMP' view of inflammatory arthritis | 2007/07/01 | English | 247 |
| Mechanisms of Disease: atherosclerosis in autoimmune diseases | 2006/02/01 | English | 245 |
| Nature and functions of autoantibodies | 2008/09/01 | English | 230 |
| Primer: inflammasomes and interleukin 1β in inflammatory disorders | 2008/01/01 | English | 225 |
| Mechanisms of Disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis | 2005/12/01 | English | 218 |
| Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? | 2008/02/05 | English | 209 |
| Technology Insight: adult stem cells in cartilage regeneration and tissue engineering | 2006/07/01 | English | 206 |
| Technology Insight: adult mesenchymal stem cells for osteoarthritis therapy | 2008/05/13 | English | 197 |
| Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor | 2006/11/01 | English | 192 |
| Behçet's syndrome: disease manifestations, management, and advances in treatment | 2007/03/01 | English | 181 |
| Mechanisms of Disease: role of chondrocytes in the pathogenesis of osteoarthritis—structure, chaos and senescence | 2007/07/01 | English | 174 |
| Biological markers in osteoarthritis | 2007/06/01 | English | 154 |
| Mechanisms of Disease: pain in fibromyalgia syndrome | 2006/02/01 | English | 146 |
| Pain measurement in patients with low back pain | 2007/11/01 | English | 145 |
| Mechanisms of Disease: pathogenesis and treatment of ANCA-associated vasculitides | 2006/12/01 | English | 143 |
| Drug Insight: tumor necrosis factor-converting enzyme as a pharmaceutical target for rheumatoid arthritis | 2008/04/15 | English | 138 |
| Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease | 2006/09/01 | English | 132 |
| Mechanisms of Disease: angiogenesis in inflammatory diseases | 2007/11/01 | English | 132 |
| Mechanisms of Disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis | 2006/08/01 | English | 131 |
| Mechanisms of Disease: the link between RANKL and arthritic bone disease | 2005/11/01 | English | 129 |
| Primer: administrative health databases in observational studies of drug effects—advantages and disadvantages | 2007/12/01 | English | 128 |
| Mechanisms and consequences of fibrosis in systemic sclerosis | 2006/03/01 | English | 128 |
| Wnt–β-catenin signaling in the pathogenesis of osteoarthritis | 2008/10/01 | English | 125 |
| The changing epidemiology of gout | 2007/08/01 | English | 124 |